Monday, September 28, 2009

OxyContin Tamper Resistant

A US Food and Drug Administration (FDA) advisory panel has recommended approval for a new formulation of controlled release oxycodone (OxyContin). As those of us in the addiction field well know Oxycontin is a significant drug of abuse with high addictive potential and dangerous and life threatening if taken in overdose. As I have mentioned before, oral opioids such as OxyContin except for alcohol and nicotine are the drugs of choice for youth today, surpassing that of marijuana. But people don't just take OxyContin orally. They crush it and then snort it, smoke it, or inject it and the physical dependence rises dramatically with this kind of use.

Purdue pharmaceuticals have made a new version of OxyContin, OxyContin TR (tamper resistant) which is designed to release less of the drug when chewed or crushed. It is supposed to turn into some kind of gel when it is dissolved in water. However, there is no current evidence to show that this formulation is safer or less abusable than the current formulation. Purdue plans to replace 90% of the OxyContin supply within 6-8 weeks of getting the final FDA approval.

Maybe it will be less abusable than the current formulation. I doubt it will be any safer. But I know someone very quickly will find a good way to use the gel it turns into and find a way to abuse it.

Thought for the day

The more things change the more they remain the same.

1 comment:

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